helicobacter pylori and migraine: is eradication of helicobacter pylori effective in relief of migraine headache?
نویسندگان
چکیده
background: association between helicobacter pylori (hp) infection and migraine and the effect of hp eradication on relief of migraine headache have been studied but the results are controversial. objectives: to evaluate the effect of hp eradication in treatment of patients affected by migraine. materials and methods: eighty consecutive hp infected patients affected by migraine without aura were enrolled in this clinical trial. they have referred to an endoscopy clinic for work-up of hp infection from october 2013 to november 2014. patients were randomly assigned in 2 groups using 2 different regimens; group a: migraine treatment and a 14-day triple therapy for hp infection and group b: migraine treatment without hp eradication. the mean duration (hour), headache severity (midas) and the frequency (per month) of clinical headache attacks were calculated upon enrollment in the study and at 6 months and 12 months after treatment. all data were analyzed using spss version 16. comparison of categorical variables across the groups was performed using chi-square test. results: in group a, hp infection was eradicated in 34 of 40 patients (85%). after treatment in eradicated patients compared with the control group there was significant decrease in severity and frequency (but not in duration) of the migraine attacks at 6 months (p<0.001) and significant decrease in intensity, frequency and duration of the migraine attacks at 12 months (p<0.001). conclusion: hp should be considered and examined in migranous patients and eradication treatment can be beneficial for relief of clinical attacks.
منابع مشابه
Helicobacter pylori and Migraine: Is Eradication of Helicobacter pylori Effective in Relief of Migraine Headache?
Background: Association between Helicobacter pylori (HP) infection and migraine and the effect of HP eradication on relief of migraine headache have been studied but the results are controversial. Objectives: To evaluate the effect of HP eradication in treatment of patients affected by migraine. Materials and Methods: Eighty consecutive HP infected patients affected by migraine without au...
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عنوان ژورنال:
caspian journal of neurological sciencesجلد ۲، شماره ۴، صفحات ۲۹-۳۵
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